Specialised Clinical Chemistry Reagents

Adenosine Deaminase (ADA)

Adenosine deaminase (ADA) assay kit is for determination of ADA activity in serum and plasma samples. The assay is linear from 0 - 200 U/L and has precisions of Intra assay %CV < 4.5% and Inter assay %CV < 5.0%.The assay is ready-to-use for both manual method and automated chemistry analyzers (Kinetic). The assay is specific for ADA and has no detectable reaction with other nucleosides and is not affected by serum bilirubin up to 30 mg/dL, heamoglobin up to 200 mg/dL, triglycerides up to 750 mg/dL, or ascorbic acid up to 4 mg/dL. The assay is based on H₂O₂ detection, which is more sensitive and reliable than the method detecting ammonia production.

Product Code: DZ117A-K -  Adenosine Deaminase Assay

Download the datasheet.

Angiotensin Converting Enzyme (ACE)

Angiotensin converting enzyme (ACE) is an enzyme which helps regulate blood pressure. It converts angiotensin I (an inactive protein) to angiotensin II which causes arteries to contract, making them temporarily narrower and increasing the pressure of the blood flowing through them. ACE is produced throughout the body, but is present in especially high amounts within the lungs.  It is normally found at a high concentration in the bloodstream of those less than 20 years of age, and will usually then drop to lower concentrations in healthy adults.

Increased amounts of ACE are sometimes produced by cells found at the outside borders of granulomas. Granulomas are a classic feature of sarcoidosis, a disorder (the cause of which is unknown) that often affects the lungs but may also affect many other body organs including the eyes, skin, nerves, liver, and heart. About 50-80% of patients with active sarcoidosis will have elevated concentrations of ACE in their bloodstream that will rise and fall as the severity of the disease changes. Granulomas, fibrosis, and an elevated ACE concentration may also be seen in infections such as leprosy and tuberculosis.

Product Code: GL309AC -  ACE Multi-Purpose Liquid Reagent

Dynamic range 5.4 U/l (0.09 μkat/l) - 166 U/l (2.8 μkat/l).

Copper (Cu)

This test measures the amount of copper in the serum and plasma. Copper is an essential mineral that the body incorporates into enzymes. These enzymes play a role in the regulation of iron metabolism, formation of connective tissue, energy production at the cellular level, the creation of melanin, and the function of the nervous system and brain.

Product Code: GL553CU -  Copper Multi-Purpose Liquid Reagent

The assay is linear up to 500 mg/dl (78.5 μmol/l).

Cystatin C

The Cystatin C Assay is an in-vitro diagnostic test for the quantitative determination of Cystatin C in serum or plasma by latex enhanced immunoturbidimetric method. The measurement of Cystatin C is used as an aid in the diagnosis and treatment of renal disease.

Product Code: GL1103CC -  Cystatin C Multi-Purpose Liquid Reagent

The assay is linear from 0.2 to 8.0 mg/L

d-Dimer

The D-Dimer Assay is for the quantitative determination of fibrinogen / fibrin degradation products (D-Dimer) in human plasma. Measurement of D-Dimer is used as an aid in detecting the presence of intravascular coagulation and fibrinolysis.

Product Code: DZ179A-K -  D-Dimer Assay

The assay is linear from 0.15 to 8.0 μg/mL FEU

Faecal Calprotectin

Two Reagent Immunoturbidimetric assay available on all leading clinical chemistry systems.

• High quality and reliability (Quantitative results)
• Cost Effective
• Ease of sampling and sample collection (Glenbio Unique FaeCollect^® devices)
• User interpretation not required
• Time to result: 15 min
• Assay Range: 20 - 8000 μg/g

The faecal calprotectin assay is a latex enhanced immunoturbidimetric assay based on the standardisation of a leading ELISA method.

The Latex Enhanced technology of immunoturbidimetry implements a significant step forward in Faecal Calprotectin quantification and a major benefit for lab technicians in terms of both time and cost saving.

The Glenbio assay can be applied on all automated platforms in the routine clinical chemistry laboratory and allows a short turn-around time from stool sample to reportable result, the introduction also of wash steps in main systems also ensures any concerns with running faecal samples on mainline systems are also addressed.

Glenbio FaeCollect^® Devices

The Glenbio FaeCollect^® devices are supplied with each kit to ensure standardisation of the collection process and to simplify the difficult process from stool collection to sample loading for the Clinical Chemistry analyser.

Product Code: GLCP101 - Glenbio FaeCalp 200^® Reagent Kit

Download the datasheet.

Vitamin D

The Diazyme EZ Vitamin D assay is intended for use in clinical laboratories for the quantitative determination of 25-OH vitamin D (vitamin D) in human serum and plasma. Measurement of vitamin D is used for the assessment of the vitamin D sufficiency. Diazyme's EZ Vitamin D Assay is the first and only 2-reagent, latex enhanced immunoturbidimetric assay for use on general clinical chemistry analysers. This new Vitamin D assay allows many clinical laboratories to run the EZ Vitamin D test in house, at a cost effective price, without the need for special instrumentation. The EZ Vitamin D assay is fully automated requiring no sample pre-treatment or pre-dilution steps and recognizes both 25-OH Vitamin D2 and D3 equally. Diazyme’s EZ Vitamin D assay ensures high assay throughput, precision CV of <10% and a linear range from 7.6 - 147.8 ng/mL. Diazyme’s EZ Vitamin D assay is CE marked, with results correlating to the LC-MS/ MS method. 

Product Code: DZ888A-K -  EZ Vitamin D Assay

Download the datasheet.

Zinc (Zn)

This test measures the amount of zinc in the serum/plasma/urine. Zinc is an essential trace element with important functions throughout the body. Zinc is important for protein synthesis, enzyme function and plays a structural role in proteins and nucleic acids. Zinc deficiency can present clinically with hair loss, poor wound healing, dermatitis and impaired immune function. In children zinc deficiency can cause growth retardation. Conditions commonly associated with zinc deficiency include: Alcoholism, pregnancy & burns. Acrodermatitis enteropathica is an inherited disorder of zinc metabolism / absorption. Zinc deficiency can be treated by supplementation and leads to improvement of clinical symptoms.

Product Code: GL535Z - Zinc Multi-Purpose Liquid Reagent

This assay is linear up to 400mg/dl (61.2 mmol/l).

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